Miss Ichijou is the Queen of Anime Oddballs.

Konata is of otaku, for otaku and by otaku.

Watabe is stepping up for the manga-fans and artists.

And poor Osaka is just too odd to be considered normal.

If you wanna talk oddball misfit, then look no further than
Mahoraba ~ Heartful Days's Occult Club President (a
personal favorite of mine)

And then there are those who sense spirits. Michiru doesn't
really DO anything odd or weird, but she's a mystic amongst
a group of very normal teenage girls.

Student Council members, like President Shizuru Fujino, are
regarded as the school's elite.

They are wise beyond their years, are admired by all the
students and faculty, and trusted to keep order.

Often they have weird plans up their sleeves.

Much like some club leaders with ulterior motives for their groups.

Others are just plain maniacal, ruling over the school and
controlling information to be later used as blackmail.

Miyagami Academy has the Best Student Council, where the
students run the school like a big-brother government.

Jindai High has a traditional student council run by some
very professional individuals.

The Big Four at Stellvia are not only regonized within the school, but the whole solar system.

Miss Sakaki is the shining example for this category. Her
academic and physical prowess make her the idol of the
school who no one feels worthy of talking to.

Natsuki, on the otherhand, chooses to be socially aloof and avoids contact with her classmates. The others in her class are pretty much afraid of her.

Makoto is also anti-social, but more in the brooding,
intolerant sort of way. People below her are a bother and
would only slow her down.

But Koyuki is another opposite... the nicest girl in school with the best grades. She's another example of someone who the other kids feel unworthy of talking to.

Then we get into the beautiful-people crowd where girls
like Tominaga enjoy the attention.

All the guys admire and want to ask out these girls, but have
that inferiority complex that makes them keep their distance.

Mirei is the belle of the Drama Club.

And Sayuri is the belle of her whole school.

Tomoe is near the top of her class.

Boys watch Yasuna's every move with admiration.

Ryoko Asakura is an A++ in comparison to the other
ichinensei/freshman girls at North High.

The pedestal Chikane's classmates put her on is so high that
she may need a helicoptor to take her seat.

Tsukasa Nishino is the blond beauty with attitude that not
just any guy can openly ask on a date.

Ayaka Machida is a top student at the Stellvia Foundation. The
only people who she'll listen to are the other top students.

If anime has taught us anything, it's that even "bad guys"
have their own struggles in life to overcome.

They usually have family issues or troubles in their past
that cause them to put up a tough front against all others.

Take Ayaka, for instance. Her brother died in a stillbirth
when Ayaka was very young. It was that event that made
her so edgy and antagonistic to anyone who stands in her
way of finding a new little brother to pamper.

Or Nao, whose promiscuity is only because of the struggles and turmoil she endured at a young age. She uses her HiME powers for uncouth reasons, but it's what makes her feel like she's gaining back what she once lost.

Miu, on the other end of the spectrum, is just insanely
jealous of her competition, but once you learn more about
her, you can begin to empathize.

Mari is also feeling the sting of jealousy, but she also becomes
someone to root for later on in the story. Love triangles are never pretty.

Lady Kirche brings obnoxious taunting to whole new heights.
Talk about a royal pain.

And Iori's burning passion for competition sets her into this
category, but she too has a caring side.

Poor Shiho, she may be annoying, but she's still human with
human feelings.

And Princess Mashiro (from Mai-Otome, not HiME) is a spoiled
brat, but hey, being the ruler of a nation has it's own stressors.

Blondes are rare in real-life Japan, so of course the "strange"
girls in anime have to be blond.

And usually if there's a young kid walking around campus,
she has a fishy story, too... especially if she's a blonde.

Skilled rivals are usually quiet and introverted... until
something weird happens, then they spring into action.

Glowing hair, weird eyes, crazy language/speech, super strength, incredible speed... some even sprout weaponery!

Mahora Academy's Chachamaru has trouble keeping her
robotic secret with her head-gear.

The maiden college intern isn't fooling anyone at Momotsuki
Academy. Who DOES she work for anyway?

Even in super-serious anime, there's always someone in the
cast to lighten the mood, like Haruna whose speech flubs and
overreaction to everything always provide plenty of humor.

Kashimashi's Jun is a cheery, rambunctious... ummm... girl?
She's always getting her classmates riled up, especially
her closest guy friend, Hachisuke.

I love Makie because bad things always happen TO her and
yet she always gets blamed for them.

The salamander from Pani Poni Dash has zero luck and he always makes his appearance when we least expect him, ~kero

Ah, what's high school drama without a little romance?

And for there to be romance, there has to be boys.

Unfortunately, the boys of anime are usually too distracted
to realize the main girl has a thing for them.

They're usually too wrapped up in a task or hobby to be paying attention to the girls vying for their attention.

Wrapping up the character archetypes are the antagonists...

Bullies!! And they seem to always travel in packs of three.